SilverStream Medical Ltd.

silverstreammed.com

Formerly EnzySurge

High-Tech Company

Graduated from: Trendlines Incubators

TECH VERTICALS

Chronic Wounds Treatment, Healthtech, Life Sciences, Medical Devices, MedTech

General Data

Sector	Medical Devices
Company Stage:	Initial Revenues
Established	2001
Number of Employees	6
Employees in Israel	4
Reg. Number:	abCDe

DESCRIPTION

Silverstream Medical is an innovative medical device company focused on transforming wound care and surgical site infection (SSI) prevention. The company's core offering, the FDA-cleared Silverstream Solution, has a proven track record in the wound management market, demonstrating safety and efficacy across over 500,000 treatments worldwide. Building on this success, Silverstream Medical is now expanding the reach into the critical surgical site infection prevention segment with precision delivery systems designed to provide unparalleled efficacy, combat antibiotic resistance, and set new standards of care in both professional surgical settings and broader wound management applications.

TECHNOLOGY

Silverstream Medical's core technology centers on its FDA-cleared Silverstream Solution, an advanced wound care formulation with proven efficacy in wound management. This innovative solution is now being enhanced through the development of two precision delivery systems: a sterile low-pressure irrigation cap kit for meticulous Surgical Site Infection (SSI) prevention in clinical settings, and a non-sterile foam applicator cap kit for controlled, sustained topical application in general wound care. These integrated systems are designed to provide unparalleled precision, actively disrupt biofilms, achieve significant pathogen reduction, and offer a safe, user-friendly application, thereby setting new standards in infection prevention and wound healing while combating the growing threat of antimicrobial resistance.

Products and Phases

Product	Phase
SilverStream	FDA Approved Approved and sold commercially in many countries
The Silverstream Solution is a patented, FDA-cleared, advanced wound management solution distinguished by its unique, synergetic formulation featuring low-volume ionic silver. Clinically validated with over 500,000 treatments and no reported adverse events, it offers comprehensive benefits beyond simple cleansing: it enhances antimicrobial activity, effectively reduces debris and disrupts stubborn biofilms, and promotes a healing environment by reducing surface tension, encouraging granulation tissue growth, and exhibiting anti-inflammatory properties. With a neutral pH that supports cellular repair and a strong safety profile—being non-toxic, non-irritating, and safe for healthy tissue—the Silverstream Solution provides over 99.9% pathogen reduction within minutes, significantly combats antibiotic resistance, and promotes efficient wound healing.
Sil.Vet	FDA Approved Approved and sold commercially in many countries
Sil.Vet Solution is a patented Wound Management Solution. It is a safe, effective, and painless treatment for wounds. It is effective against a wide range of bacteria, fungi, and even those resistant to antibiotics. Sil.Vet Solution is made up of a low concentration of silver ions, menthol, glycerol, and a surfactant, dissolved in a hypertonic solution. Sil.Vet Solution is safe for use on all animals, including pets but excluding Livestock. It is also ideal for use in a first aid kit.

TARGET MARKETS

Silverstream Medical targeted customers span the entire healthcare spectrum, from professional medical environments like hospitals, surgical centers, and wound care clinics—where our precision delivery systems will revolutionize Surgical Site Infection (SSI) prevention and advanced wound management for healthcare professionals—to the broader consumer market, where our user-friendly foam applicator kit will empower patients with effective home wound care solutions, all distributed through established healthcare networks and direct-to-consumer channels

	BUSINESS MODEL
	B2B

CONTACT INFO

Expand / Collapse All

Main Address: Caesarea, Israel

Address	11 Hof Hazahav St.
City	Caesarea
Country	Israel
Zip	3089900

Contact Person	abC Defghij
Company E-mail	abC Defghij
Telephone	abC Defghij
Fax	abC Defghij

Branch Address: Atlanta, United States

Address	1190 N Highland Ave.
City	Atlanta
State/Province	GA
Country	United States
Zip	30306-9997

Contact Person	abC Defghij
Company E-mail	abC Defghij
Telephone	abC Defghij
Fax	abC Defghij

	MANAGEMENT

Key Executive

Name	Title	Previous Position
Mr. Eyal Nouri	CEO & Founder	Pango Pay & Go (VP, Business Development)
Ms. Elya Presman	COO & Co-Founder
Mr. Alon Raivit	VP, Business Development & Co-Founder
Prof. Amihay Freeman	Co-Founder

	BOARD

Board

Member	Title	Affiliation
abC Defghij	Chairman	CEO & Co-Founder, SilverStream Medical
abC Defghij	Board Member	VP, Business Development & Co-Founder, SilverStream Medical

	FINANCIAL ROUNDS

Total Capital Raised
abCDe

Financial Rounds

Numbers of Investors

Expand / Collapse All

Round

Date

Stage

Amount

Valuation

Fifth Round

Dec. 22, 2009

Initial Revenues

abCDe

Fourth Round - Extended

Jun. 02, 2008

R&D

abCDe

* New investor

Investor	Type	Amount	Remarks
abC Defghij	Investment Company	abCDe
abC Defghij	Private Investor	abCDe

Fourth Round

Jan. 08, 2008

R&D

abCDe

* New investor

Investor	Type	Amount	Remarks
abC Defghij	Investment Company	abCDe
abC Defghij	Other	abCDe
abC Defghij	Private Investor	abCDe

Third Round

Dec. 31, 2006

R&D

abCDe

Second Round

Oct. 09, 2005

R&D

abCDe

First Round

Oct. 26, 2004

R&D

abCDe

* New investor

Investor	Type	Amount	Remarks
abC Defghij*	Venture Capital Fund	abCDe	Holdings sold.
abC Defghij	Private Investor	abCDe
abC Defghij	Private Investor	abCDe

Seed

Oct. 01, 2001

Seed

abCDe

* New investor

Investor	Type	Amount	Remarks
abC Defghij	Technology Transfer Company	abCDe
abC Defghij	Government Agency	abCDe	R&D Grant
abC Defghij	Incubator	abCDe

Last Updated:	abCDe
IVC Number:	abCDe